Atomistry » Thallium » PDB 1f1h-4wfh » 1nv2
Atomistry »
  Thallium »
    PDB 1f1h-4wfh »
      1nv2 »

Thallium in PDB 1nv2: Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)

Enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)

All present enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm):
3.1.3.11;

Protein crystallography data

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm), PDB code: 1nv2 was solved by J.Choe, C.V.Iancu, H.J.Fromm, R.B.Honzatko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 5.00 / 2.10
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 52.361, 82.765, 165.288, 90.00, 90.00, 90.00
R / Rfree (%) 17.8 / 24.8

Other elements in 1nv2:

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Thallium Binding Sites:

The binding sites of Thallium atom in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) (pdb code 1nv2). This binding sites where shown within 5.0 Angstroms radius around Thallium atom.
In total 6 binding sites of Thallium where determined in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm), PDB code: 1nv2:
Jump to Thallium binding site number: 1; 2; 3; 4; 5; 6;

Thallium binding site 1 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 1 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 1 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2342

b:17.8
occ:0.04
MG A:MG2341 0.4 36.7 0.6
OD1 A:ASP1121 1.8 17.5 1.0
O2 A:PI2340 2.0 39.1 1.0
OE1 A:GLU1280 2.0 22.6 1.0
OD1 A:ASP1118 2.2 27.3 1.0
O3 A:PI2340 2.7 26.9 1.0
OE2 A:GLU1097 2.7 38.4 1.0
P A:PI2340 2.8 34.9 1.0
CG A:ASP1121 2.9 22.9 1.0
CD A:GLU1280 3.2 19.8 1.0
CG A:ASP1118 3.2 24.3 1.0
O1 A:PI2340 3.4 26.2 1.0
CB A:ASP1121 3.5 23.1 1.0
OD2 A:ASP1118 3.6 26.9 1.0
CD A:GLU1097 3.6 32.5 1.0
CG A:GLU1280 3.8 11.2 1.0
C1 A:F6P2339 3.8 22.4 1.0
OE1 A:GLU1097 3.9 22.9 1.0
CA A:ASP1121 3.9 24.4 1.0
TL A:TL2344 3.9 30.7 0.1
MG A:MG2343 3.9 34.5 0.5
TL A:TL2347 4.0 25.2 0.3
OD2 A:ASP1121 4.0 23.6 1.0
O1 A:F6P2339 4.0 24.5 1.0
O4 A:PI2340 4.1 39.9 1.0
TL A:TL2348 4.1 32.0 0.2
OE2 A:GLU1280 4.2 19.4 1.0
CB A:ASP1118 4.4 14.6 1.0
O A:LEU1120 4.5 10.9 1.0
N A:GLY1122 4.7 25.4 1.0
C A:ASP1121 4.8 27.8 1.0
C2 A:F6P2339 4.9 25.9 1.0
N A:ASP1121 4.9 11.6 1.0
O2 A:F6P2339 5.0 17.9 1.0
CG A:GLU1097 5.0 22.6 1.0
O3 A:F6P2339 5.0 21.8 1.0

Thallium binding site 2 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 2 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 2 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2344

b:30.7
occ:0.07
MG A:MG2343 0.0 34.5 0.5
OE1 A:GLU1097 1.9 22.9 1.0
O A:LEU1120 2.1 10.9 1.0
O2 A:PI2340 2.4 39.1 1.0
OD2 A:ASP1118 2.4 26.9 1.0
CD A:GLU1097 3.0 32.5 1.0
O4 A:PI2340 3.1 39.9 1.0
C A:LEU1120 3.2 23.6 1.0
P A:PI2340 3.3 34.9 1.0
CG A:ASP1118 3.5 24.3 1.0
TL A:TL2346 3.5 25.5 0.2
OE2 A:GLU1097 3.5 38.4 1.0
OE2 A:GLU1098 3.5 34.6 1.0
MG A:MG2341 3.5 36.7 0.6
OD1 A:ASP1074 3.7 33.0 1.0
TL A:TL2345 3.7 27.2 0.2
OD1 A:ASP1118 3.8 27.3 1.0
TL A:TL2342 3.9 17.8 0.0
N A:LEU1120 4.1 17.3 1.0
N A:ASP1121 4.1 11.6 1.0
CA A:ASP1121 4.1 24.4 1.0
O3 A:PI2340 4.1 26.9 1.0
CA A:LEU1120 4.1 24.1 1.0
CG A:GLU1097 4.2 22.6 1.0
O1 A:PI2340 4.5 26.2 1.0
CG A:ASP1074 4.5 23.7 1.0
CB A:LEU1120 4.6 18.8 1.0
CB A:GLU1097 4.7 16.6 1.0
CD A:PRO1119 4.7 13.3 1.0
CD A:GLU1098 4.7 22.8 1.0
CB A:ASP1118 4.8 14.6 1.0
OG A:SER1123 4.8 33.9 1.0
CB A:ASP1121 4.9 23.1 1.0
OD2 A:ASP1074 4.9 42.8 1.0
N A:PRO1119 4.9 16.1 1.0

Thallium binding site 3 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 3 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 3 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2345

b:27.2
occ:0.25
OE2 A:GLU1098 2.5 34.6 1.0
ND2 A:ASN1064 2.8 56.5 1.0
OE1 A:GLU1097 3.0 22.9 1.0
OE1 A:GLU1098 3.2 31.4 1.0
CD A:GLU1098 3.2 22.8 1.0
CD A:GLU1097 3.6 32.5 1.0
O4 A:PI2340 3.7 39.9 1.0
TL A:TL2344 3.7 30.7 0.1
CG A:ASN1064 3.8 70.7 1.0
MG A:MG2343 3.8 34.5 0.5
OD2 A:ASP1074 3.9 42.8 1.0
CG A:GLU1097 4.0 22.6 1.0
OD2 A:ASP1068 4.1 84.7 1.0
CB A:ASP1068 4.1 86.5 1.0
OD1 A:ASN1064 4.3 70.1 1.0
CG A:ASP1074 4.3 23.7 1.0
OE2 A:GLU1097 4.5 38.4 1.0
OD1 A:ASP1074 4.5 33.0 1.0
CG A:ASP1068 4.6 88.5 1.0
CG A:GLU1098 4.7 21.7 1.0
P A:PI2340 4.7 34.9 1.0
CB A:ASN1064 4.7 77.8 1.0
O3 A:PI2340 4.8 26.9 1.0
OG A:SER1123 4.9 33.9 1.0
O2 A:PI2340 5.0 39.1 1.0

Thallium binding site 4 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 4 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 4 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2346

b:25.5
occ:0.25
OG A:SER1123 2.5 33.9 1.0
OD1 A:ASP1074 2.7 33.0 1.0
O A:LEU1120 2.8 10.9 1.0
O4 A:PI2340 3.2 39.9 1.0
CG A:ASP1074 3.4 23.7 1.0
OD2 A:ASP1074 3.5 42.8 1.0
TL A:TL2344 3.5 30.7 0.1
MG A:MG2343 3.5 34.5 0.5
CA A:SER1123 3.6 29.7 1.0
CB A:SER1123 3.6 24.7 1.0
C A:LEU1120 3.6 23.6 1.0
N A:SER1123 3.7 24.4 1.0
CB A:LEU1120 3.9 18.8 1.0
P A:PI2340 4.0 34.9 1.0
O2 A:PI2340 4.1 39.1 1.0
O1 A:PI2340 4.3 26.2 1.0
CG A:LEU1120 4.3 21.0 1.0
CD2 A:LEU1120 4.4 24.5 1.0
N A:GLY1122 4.4 25.4 1.0
CA A:LEU1120 4.4 24.1 1.0
N A:ASP1121 4.4 11.6 1.0
CA A:ASP1121 4.5 24.4 1.0
C A:GLY1122 4.5 22.4 1.0
C A:ASP1121 4.6 27.8 1.0
CG1 A:ILE1126 4.8 18.4 1.0
CB A:ASP1074 4.9 21.2 1.0
CG A:LYS1071 4.9 40.6 1.0
CD1 A:ILE1126 4.9 28.2 1.0

Thallium binding site 5 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 5 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 5 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2347

b:25.2
occ:0.30
TL A:TL2348 2.5 32.0 0.2
OE2 A:GLU1097 2.7 38.4 1.0
O3 A:PI2340 2.8 26.9 1.0
OD2 A:ASP1068 3.4 84.7 1.0
OE1 A:GLU1280 3.5 22.6 1.0
CD A:GLU1097 3.5 32.5 1.0
NE A:ARG1276 3.6 37.0 1.0
MG A:MG2341 3.7 36.7 0.6
O1 A:F6P2339 3.8 24.5 1.0
CG A:ARG1276 3.9 15.6 1.0
TL A:TL2342 4.0 17.8 0.0
CG A:GLU1097 4.1 22.6 1.0
CG A:ASP1068 4.2 88.5 1.0
P A:PI2340 4.2 34.9 1.0
NH1 A:ARG1276 4.3 33.7 1.0
CD A:GLU1280 4.3 19.8 1.0
CD A:ARG1276 4.4 24.9 1.0
OE1 A:GLU1097 4.4 22.9 1.0
CZ A:ARG1276 4.4 41.6 1.0
OE2 A:GLU1280 4.4 19.4 1.0
O2 A:PI2340 4.6 39.1 1.0
OD1 A:ASP1068 4.7 0.8 1.0
C1 A:F6P2339 4.7 22.4 1.0
O4 A:PI2340 4.8 39.9 1.0

Thallium binding site 6 out of 6 in 1nv2

Go back to Thallium Binding Sites List in 1nv2
Thallium binding site 6 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 6 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2348

b:32.0
occ:0.18
TL A:TL2347 2.5 25.2 0.3
O1 A:F6P2339 2.8 24.5 1.0
OE2 A:GLU1280 2.9 19.4 1.0
OE1 A:GLU1280 2.9 22.6 1.0
C1 A:F6P2339 3.2 22.4 1.0
CD A:GLU1280 3.3 19.8 1.0
O3 A:PI2340 3.6 26.9 1.0
O A:LYS1274 3.9 14.0 1.0
CG A:ARG1276 3.9 15.6 1.0
CA A:LEU1275 4.0 12.7 1.0
TL A:TL2342 4.1 17.8 0.0
CD2 A:LEU1275 4.1 13.5 1.0
MG A:MG2341 4.1 36.7 0.6
CE A:LYS1274 4.2 18.8 1.0
NE A:ARG1276 4.2 37.0 1.0
CG A:LYS1274 4.2 17.3 1.0
OE2 A:GLU1097 4.3 38.4 1.0
N A:ARG1276 4.3 25.7 1.0
C A:LYS1274 4.5 11.6 1.0
CD A:ARG1276 4.6 24.9 1.0
N A:LEU1275 4.6 10.9 1.0
C A:LEU1275 4.6 20.3 1.0
C2 A:F6P2339 4.7 25.9 1.0
NH1 A:ARG1313 4.7 45.0 1.0
CD A:LYS1274 4.8 15.2 1.0
CG A:GLU1280 4.8 11.2 1.0
OD2 A:ASP1068 4.8 84.7 1.0
CB A:LEU1275 4.8 11.1 1.0
P A:PI2340 4.9 34.9 1.0
OD1 A:ASP1121 5.0 17.5 1.0

Reference:

J.Y.Choe, S.W.Nelson, H.J.Fromm, R.B.Honzatko. Interaction of Tl+ with Product Complexes of Fructose-1,6-Bisphosphatase J.Biol.Chem. V. 278 16008 2003.
ISSN: ISSN 0021-9258
PubMed: 12595529
DOI: 10.1074/JBC.M212394200
Page generated: Wed Dec 16 02:28:32 2020

Last articles

Sr in 3I55
Sr in 3G71
Sr in 3I5A
Sr in 3G6E
Sr in 3G4S
Sr in 3GOO
Sr in 3CPW
Sr in 3CME
Sr in 3CMA
Sr in 3EY3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy