Atomistry » Thallium » PDB 1f1h-4wfh » 1nv5
Atomistry »
  Thallium »
    PDB 1f1h-4wfh »
      1nv5 »

Thallium in PDB 1nv5: Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)

Enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)

All present enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm):
3.1.3.11;

Protein crystallography data

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm), PDB code: 1nv5 was solved by J.Choe, C.V.Iancu, H.J.Fromm, R.B.Honzatko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 5.00 / 1.90
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 53.074, 82.829, 165.173, 90.00, 90.00, 90.00
R / Rfree (%) 19.7 / 24.5

Other elements in 1nv5:

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Thallium Binding Sites:

The binding sites of Thallium atom in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) (pdb code 1nv5). This binding sites where shown within 5.0 Angstroms radius around Thallium atom.
In total 6 binding sites of Thallium where determined in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm), PDB code: 1nv5:
Jump to Thallium binding site number: 1; 2; 3; 4; 5; 6;

Thallium binding site 1 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 1 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 1 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2342

b:23.5
occ:0.06
 MG A:MG2341 0.6 22.8 0.9
OD1 A:ASP1121 1.6 14.9 1.0
OD1 A:ASP1118 2.2 22.8 1.0
CG A:ASP1121 2.4 22.0 1.0
O2 A:PO42340 2.4 26.7 1.0
OE1 A:GLU1280 2.4 21.5 1.0
CB A:ASP1121 2.7 18.4 1.0
O1 A:F6P2339 2.8 14.2 0.5
CA A:ASP1121 3.2 21.0 1.0
CG A:ASP1118 3.4 22.5 1.0
CD A:GLU1280 3.5 27.3 1.0
OD2 A:ASP1121 3.6 18.3 1.0
P A:PO42340 3.6 24.8 1.0
O3 A:F6P2339 3.7 19.6 1.0
O1 A:PO42340 3.8 14.7 1.0
CG A:GLU1280 3.9 13.9 1.0
C1 A:F6P2339 3.9 19.5 1.0
TL A:TL2344 3.9 8.3 0.1
OD2 A:ASP1118 3.9 16.6 1.0
N A:GLY1122 4.0 18.8 1.0
C A:ASP1121 4.0 24.2 1.0
CD1 A:ILE1135 4.1 25.8 1.0
O3 A:PO42340 4.1 28.3 1.0
C3 A:F6P2339 4.3 25.7 1.0
N A:ASP1121 4.4 10.9 1.0
CB A:ASP1118 4.5 15.7 1.0
C2 A:F6P2339 4.5 28.3 1.0
OE2 A:GLU1280 4.6 19.3 1.0
O A:LEU1120 4.7 15.6 1.0
OE2 A:GLU1097 4.7 20.1 1.0
O2 A:F6P2339 4.7 21.3 1.0
MG A:MG2343 4.7 28.6 0.7
O4 A:PO42340 4.8 40.8 1.0
O1 A:F6P2339 4.8 8.3 0.5
C A:LEU1120 4.9 10.8 1.0

Thallium binding site 2 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 2 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 2 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2344

b:8.3
occ:0.06
 MG A:MG2343 0.8 28.6 0.7
OD2 A:ASP1118 1.9 16.6 1.0
OE2 A:GLU1097 2.0 20.1 1.0
O2 A:PO42340 2.0 26.7 1.0
O A:LEU1120 2.2 15.6 1.0
O4 A:PO42340 2.4 40.8 1.0
P A:PO42340 2.7 24.8 1.0
CG A:ASP1118 2.8 22.5 1.0
CD A:GLU1097 3.1 21.7 1.0
OD1 A:ASP1118 3.2 22.8 1.0
C A:LEU1120 3.2 10.8 1.0
OE1 A:GLU1097 3.5 28.2 1.0
MG A:MG2341 3.6 22.8 0.9
O3 A:PO42340 3.7 28.3 1.0
CA A:ASP1121 3.8 21.0 1.0
O1 A:PO42340 3.9 14.7 1.0
N A:ASP1121 3.9 10.9 1.0
TL A:TL2342 3.9 23.5 0.1
TL A:TL2346 3.9 24.2 0.1
N A:LEU1120 4.1 13.5 1.0
TL A:TL2345 4.2 26.9 0.1
CB A:ASP1118 4.2 15.7 1.0
CA A:LEU1120 4.3 21.5 1.0
OE2 A:GLU1098 4.4 23.2 1.0
CG A:GLU1097 4.4 17.1 1.0
OD1 A:ASP1074 4.4 31.5 1.0
CB A:ASP1121 4.5 18.4 1.0
CB A:GLU1097 4.6 14.6 1.0
CA A:ASP1118 4.7 15.5 1.0
O1 A:F6P2339 4.7 14.2 0.5
C A:ASP1118 4.7 13.3 1.0
CD A:PRO1119 4.8 13.2 1.0
C A:ASP1121 4.9 24.2 1.0
N A:PRO1119 4.9 17.8 1.0
CB A:LEU1120 4.9 21.5 1.0
OE1 A:GLU1280 5.0 21.5 1.0
N A:GLY1122 5.0 18.8 1.0

Thallium binding site 3 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 3 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 3 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2345

b:26.9
occ:0.08
 OE2 A:GLU1098 2.4 23.2 1.0
OE1 A:GLU1097 2.7 28.2 1.0
ND2 A:ASN1064 2.9 48.8 1.0
CD A:GLU1097 3.3 21.7 1.0
O4 A:PO42340 3.3 40.8 1.0
CD A:GLU1098 3.4 27.0 1.0
OE1 A:GLU1098 3.6 28.6 1.0
OD2 A:ASP1068 3.7 56.4 1.0
CG A:ASN1064 3.7 63.7 1.0
OE2 A:GLU1097 3.7 20.1 1.0
OD2 A:ASP1074 3.7 33.2 1.0
MG A:MG2343 3.7 28.6 0.7
CG A:ASP1068 3.8 64.5 1.0
OD1 A:ASN1064 3.9 79.1 1.0
CG A:ASP1074 4.0 30.3 1.0
OD1 A:ASP1068 4.0 78.3 1.0
CG A:GLU1097 4.1 17.1 1.0
OD1 A:ASP1074 4.2 31.5 1.0
TL A:TL2344 4.2 8.3 0.1
P A:PO42340 4.4 24.8 1.0
O3 A:PO42340 4.5 28.3 1.0
CB A:ASP1068 4.5 68.7 1.0
TL A:TL2346 4.7 24.2 0.1
CG A:GLU1098 4.8 19.2 1.0
CB A:ASN1064 4.8 61.0 1.0
CB A:ASP1074 4.9 26.8 1.0
CG2 A:VAL1070 4.9 61.8 1.0

Thallium binding site 4 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 4 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 4 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2346

b:24.2
occ:0.10
 OD1 A:ASP1074 2.6 31.5 1.0
O4 A:PO42340 2.8 40.8 1.0
O A:LEU1120 2.9 15.6 1.0
CB A:SER1123 3.0 18.4 1.0
CA A:SER1123 3.2 21.7 1.0
OG A:SER1123 3.4 40.3 1.0
CG A:ASP1074 3.5 30.3 1.0
N A:SER1123 3.5 20.6 1.0
OD2 A:ASP1074 3.6 33.2 1.0
MG A:MG2343 3.7 28.6 0.7
C A:LEU1120 3.8 10.8 1.0
P A:PO42340 3.8 24.8 1.0
O1 A:PO42340 3.9 14.7 1.0
TL A:TL2344 3.9 8.3 0.1
CB A:LEU1120 3.9 21.5 1.0
CG A:LEU1120 4.1 18.6 1.0
CD2 A:LEU1120 4.2 30.4 1.0
C A:GLY1122 4.4 15.4 1.0
N A:GLY1122 4.5 18.8 1.0
O2 A:PO42340 4.5 26.7 1.0
CA A:LEU1120 4.5 21.5 1.0
N A:ASP1121 4.6 10.9 1.0
C A:ASP1121 4.7 24.2 1.0
C A:SER1123 4.7 22.4 1.0
CA A:ASP1121 4.7 21.0 1.0
TL A:TL2345 4.7 26.9 0.1
CG1 A:ILE1126 4.7 18.1 1.0
CB A:ASP1074 4.9 26.8 1.0
CG A:LYS1071 4.9 35.0 1.0

Thallium binding site 5 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 5 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 5 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2347

b:29.1
occ:0.11
 TL A:TL2348 2.5 29.2 0.1
OE1 A:GLU1097 2.9 28.2 1.0
O3 A:PO42340 3.2 28.3 1.0
CD A:GLU1097 3.5 21.7 1.0
NE A:ARG1276 3.5 42.9 1.0
CG A:ARG1276 3.7 29.6 1.0
OD2 A:ASP1068 3.8 56.4 1.0
O1 A:F6P2339 3.9 8.3 0.5
CG A:GLU1097 4.0 17.1 1.0
OE1 A:GLU1280 4.0 21.5 1.0
OE2 A:GLU1280 4.0 19.3 1.0
OE2 A:GLU1097 4.1 20.1 1.0
CD A:ARG1276 4.3 37.7 1.0
CD A:GLU1280 4.3 27.3 1.0
O1 A:F6P2339 4.4 14.2 0.5
NH1 A:ARG1276 4.4 30.4 1.0
CZ A:ARG1276 4.4 40.8 1.0
P A:PO42340 4.5 24.8 1.0
O2 A:PO42340 4.6 26.7 1.0
C1 A:F6P2339 4.6 19.5 1.0
CG A:ASP1068 5.0 64.5 1.0
CE1 A:TYR1279 5.0 17.0 1.0

Thallium binding site 6 out of 6 in 1nv5

Go back to Thallium Binding Sites List in 1nv5
Thallium binding site 6 out of 6 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 6 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (5 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2348

b:29.2
occ:0.10
 TL A:TL2347 2.5 29.1 0.1
OE2 A:GLU1280 2.7 19.3 1.0
O1 A:F6P2339 3.1 8.3 0.5
OE1 A:GLU1280 3.3 21.5 1.0
C1 A:F6P2339 3.3 19.5 1.0
CD A:GLU1280 3.4 27.3 1.0
O A:LYS1274 3.7 20.1 1.0
O1 A:F6P2339 3.8 14.2 0.5
CG A:ARG1276 3.8 29.6 1.0
CA A:LEU1275 3.9 18.0 1.0
O3 A:PO42340 4.0 28.3 1.0
CD2 A:LEU1275 4.1 19.6 1.0
CE A:LYS1274 4.1 23.6 1.0
N A:ARG1276 4.1 20.2 1.0
NE A:ARG1276 4.2 42.9 1.0
CG A:LYS1274 4.2 20.7 1.0
C A:LYS1274 4.3 12.5 1.0
C A:LEU1275 4.4 24.4 1.0
N A:LEU1275 4.5 14.9 1.0
CD A:ARG1276 4.5 37.7 1.0
CD A:LYS1274 4.6 14.6 1.0
CB A:LEU1275 4.7 18.1 1.0
C2 A:F6P2339 4.8 28.3 1.0
NH1 A:ARG1313 4.8 23.3 1.0
MG A:MG2341 4.8 22.8 0.9
CB A:ARG1276 4.9 16.3 1.0
CG A:GLU1280 4.9 13.9 1.0

Reference:

J.Y.Choe, S.W.Nelson, H.J.Fromm, R.B.Honzatko. Interaction of Tl+ with Product Complexes of Fructose-1,6-Bisphosphatase J.Biol.Chem. V. 278 16008 2003.
ISSN: ISSN 0021-9258
PubMed: 12595529
DOI: 10.1074/JBC.M212394200
Page generated: Fri Oct 11 09:28:24 2024

Last articles

Cl in 3OWL
Cl in 3OWK
Cl in 3OWD
Cl in 3OWB
Cl in 3OUI
Cl in 3OVX
Cl in 3OVZ
Cl in 3OV8
Cl in 3OVE
Cl in 3OUH
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy