Atomistry » Thallium » PDB 1f1h-4wfh » 1nv6
Atomistry »
  Thallium »
    PDB 1f1h-4wfh »
      1nv6 »

Thallium in PDB 1nv6: Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)

Enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)

All present enzymatic activity of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm):
3.1.3.11;

Protein crystallography data

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm), PDB code: 1nv6 was solved by J.Choe, C.V.Iancu, H.J.Fromm, R.B.Honzatko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 5.00 / 2.15
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 53.074, 82.829, 165.173, 90.00, 90.00, 90.00
R / Rfree (%) 21.8 / 28

Other elements in 1nv6:

The structure of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Thallium Binding Sites:

The binding sites of Thallium atom in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) (pdb code 1nv6). This binding sites where shown within 5.0 Angstroms radius around Thallium atom.
In total 5 binding sites of Thallium where determined in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm), PDB code: 1nv6:
Jump to Thallium binding site number: 1; 2; 3; 4; 5;

Thallium binding site 1 out of 5 in 1nv6

Go back to Thallium Binding Sites List in 1nv6
Thallium binding site 1 out of 5 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 1 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2342

b:25.1
occ:0.06
 MG A:MG2343 0.8 28.5 0.6
OD2 A:ASP1118 1.7 24.9 1.0
O2 A:PI2340 1.8 41.0 1.0
OE1 A:GLU1097 2.1 30.5 1.0
O A:LEU1120 2.5 22.2 1.0
CD A:GLU1097 2.6 32.5 1.0
OE2 A:GLU1097 2.7 44.6 1.0
CG A:ASP1118 2.8 27.6 1.0
MG A:MG2341 3.1 21.8 0.8
P A:PI2340 3.1 33.1 1.0
OD1 A:ASP1118 3.3 23.4 1.0
C A:LEU1120 3.5 23.1 1.0
O3 A:PI2340 3.6 35.7 1.0
O4 A:PI2340 3.6 42.2 1.0
CA A:ASP1121 3.9 29.7 1.0
CG A:GLU1097 3.9 37.1 1.0
OE2 A:GLU1098 4.0 31.0 1.0
CB A:ASP1118 4.1 24.7 1.0
TL A:TL2344 4.1 26.9 0.1
N A:ASP1121 4.1 18.8 1.0
CB A:GLU1097 4.2 28.3 1.0
O1 A:PI2340 4.2 22.6 1.0
TL A:TL2345 4.2 28.4 0.2
N A:LEU1120 4.2 31.0 1.0
OD1 A:ASP1121 4.3 15.6 1.0
CA A:LEU1120 4.4 32.9 1.0
CB A:ASP1121 4.5 28.3 1.0
CA A:ASP1118 4.5 27.9 1.0
C A:ASP1118 4.6 11.2 1.0
OD1 A:ASP1074 4.7 49.7 1.0
CD A:PRO1119 4.8 17.1 1.0
N A:PRO1119 4.8 18.1 1.0
OE1 A:GLU1280 4.8 30.9 1.0
CG A:ASP1121 4.8 26.8 1.0

Thallium binding site 2 out of 5 in 1nv6

Go back to Thallium Binding Sites List in 1nv6
Thallium binding site 2 out of 5 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 2 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2344

b:26.9
occ:0.13
 ND2 A:ASN1064 2.5 86.9 1.0
OE2 A:GLU1098 2.5 31.0 1.0
OE1 A:GLU1097 2.7 30.5 1.0
CG A:ASN1064 3.0 0.3 1.0
OD1 A:ASN1064 3.1 0.5 1.0
CD A:GLU1098 3.2 24.2 1.0
OE1 A:GLU1098 3.3 27.8 1.0
MG A:MG2343 3.7 28.5 0.6
CD A:GLU1097 3.7 32.5 1.0
OD2 A:ASP1074 3.7 43.9 1.0
OD2 A:ASP1068 3.8 62.0 1.0
O4 A:PI2340 3.8 42.2 1.0
CB A:ASP1068 4.0 61.6 1.0
CG A:ASP1074 4.1 36.9 1.0
TL A:TL2342 4.1 25.1 0.1
CG A:GLU1097 4.3 37.1 1.0
OD1 A:ASP1074 4.3 49.7 1.0
CB A:ASN1064 4.3 0.0 1.0
CG A:ASP1068 4.4 58.9 1.0
OE2 A:GLU1097 4.6 44.6 1.0
O2 A:PI2340 4.7 41.0 1.0
P A:PI2340 4.7 33.1 1.0
CG A:GLU1098 4.7 17.4 1.0
O3 A:PI2340 4.8 35.7 1.0
CB A:GLU1097 4.9 28.3 1.0
CB A:ASP1074 4.9 26.2 1.0
OG A:SER1123 5.0 36.5 1.0

Thallium binding site 3 out of 5 in 1nv6

Go back to Thallium Binding Sites List in 1nv6
Thallium binding site 3 out of 5 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 3 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2345

b:28.4
occ:0.21
 OD1 A:ASP1074 2.6 49.7 1.0
OG A:SER1123 2.7 36.5 1.0
O A:LEU1120 2.9 22.2 1.0
O4 A:PI2340 3.2 42.2 1.0
CA A:SER1123 3.4 27.9 1.0
CB A:SER1123 3.4 26.7 1.0
N A:SER1123 3.5 24.1 1.0
CG A:ASP1074 3.6 36.9 1.0
O2 A:PI2340 3.7 41.0 1.0
MG A:MG2343 3.7 28.5 0.6
C A:LEU1120 3.7 23.1 1.0
OD2 A:ASP1074 3.8 43.9 1.0
P A:PI2340 3.9 33.1 1.0
CB A:LEU1120 4.0 23.8 1.0
TL A:TL2342 4.2 25.1 0.1
O1 A:PI2340 4.2 22.6 1.0
CG A:LEU1120 4.3 27.4 1.0
N A:GLY1122 4.4 30.7 1.0
C A:GLY1122 4.4 20.8 1.0
CA A:ASP1121 4.5 29.7 1.0
N A:ASP1121 4.5 18.8 1.0
CA A:LEU1120 4.5 32.9 1.0
CD2 A:LEU1120 4.5 37.0 1.0
C A:ASP1121 4.5 35.9 1.0
C A:SER1123 4.8 28.3 1.0
CG1 A:ILE1126 4.8 31.3 1.0
CG A:LYS1071 5.0 47.4 1.0
CB A:ASP1074 5.0 26.2 1.0

Thallium binding site 4 out of 5 in 1nv6

Go back to Thallium Binding Sites List in 1nv6
Thallium binding site 4 out of 5 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 4 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2351

b:29.2
occ:0.26
 TL A:TL2352 2.5 29.3 0.1
O3 A:PI2340 2.8 35.7 1.0
OE2 A:GLU1097 2.9 44.6 1.0
O A:HOH3060 3.3 27.1 1.0
CD A:GLU1097 3.4 32.5 1.0
OD2 A:ASP1068 3.6 62.0 1.0
NE A:ARG1276 3.7 38.8 1.0
OE1 A:GLU1280 3.9 30.9 1.0
CG A:GLU1097 3.9 37.1 1.0
O1 A:F6P2339 4.0 31.2 1.0
OE1 A:GLU1097 4.0 30.5 1.0
CG A:ARG1276 4.0 14.5 1.0
CG A:ASP1068 4.1 58.9 1.0
MG A:MG2341 4.1 21.8 0.8
P A:PI2340 4.2 33.1 1.0
OD1 A:ASP1068 4.3 71.6 1.0
NH1 A:ARG1276 4.4 50.3 1.0
CD A:ARG1276 4.4 28.5 1.0
OE2 A:GLU1280 4.5 34.2 1.0
CD A:GLU1280 4.5 23.3 1.0
CZ A:ARG1276 4.5 42.0 1.0
C1 A:F6P2339 4.7 26.8 1.0
O4 A:PI2340 4.7 42.2 1.0
O2 A:PI2340 4.8 41.0 1.0
ND2 A:ASN1064 4.9 86.9 1.0

Thallium binding site 5 out of 5 in 1nv6

Go back to Thallium Binding Sites List in 1nv6
Thallium binding site 5 out of 5 in the Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm)


Mono view


Stereo pair view

A full contact list of Thallium with other atoms in the Tl binding site number 5 of Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6- Phosphate, Phosphate, Edta and Thallium (20 Mm) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Tl2352

b:29.3
occ:0.15
 TL A:TL2351 2.5 29.2 0.3
O1 A:F6P2339 3.1 31.2 1.0
OE2 A:GLU1280 3.1 34.2 1.0
C1 A:F6P2339 3.3 26.8 1.0
OE1 A:GLU1280 3.4 30.9 1.0
O A:HOH3060 3.4 27.1 1.0
CD A:GLU1280 3.7 23.3 1.0
O3 A:PI2340 3.7 35.7 1.0
O A:LYS1274 3.7 24.8 1.0
CE A:LYS1274 3.8 26.3 1.0
CG A:ARG1276 4.0 14.5 1.0
CA A:LEU1275 4.1 26.1 1.0
CD2 A:LEU1275 4.2 16.0 1.0
CG A:LYS1274 4.2 21.6 1.0
NE A:ARG1276 4.2 38.8 1.0
CD A:ARG1276 4.3 28.5 1.0
C A:LYS1274 4.4 18.7 1.0
CD A:LYS1274 4.4 21.5 1.0
N A:ARG1276 4.4 28.4 1.0
MG A:MG2341 4.5 21.8 0.8
OE2 A:GLU1097 4.5 44.6 1.0
N A:LEU1275 4.6 24.1 1.0
NH1 A:ARG1313 4.6 38.8 1.0
C A:LEU1275 4.7 27.4 1.0
C2 A:F6P2339 4.8 32.6 1.0
CB A:LEU1275 5.0 18.6 1.0

Reference:

J.Y.Choe, S.W.Nelson, H.J.Fromm, R.B.Honzatko. Interaction of Tl+ with Product Complexes of Fructose-1,6-Bisphosphatase J.Biol.Chem. V. 278 16008 2003.
ISSN: ISSN 0021-9258
PubMed: 12595529
DOI: 10.1074/JBC.M212394200
Page generated: Fri Oct 11 09:28:26 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy